John Isner of the US reacts to a lost point during his match against Thiemo de Bakker of Netherland's at the All England Lawn Tennis Championships at Wimbledon, Friday, June 25, 2010.
The Wimbledon marathon man looked weary from the outset Friday, required treatment for a neck injury and was beaten by unseeded Thiemo de Bakker 6-0, 6-3, 6-2.
